De-Risking Gene Therapy Development - Stress Testing Viral Vectors with Mass Photometry Analysis

Learn how to apply mass photometry analysis as a powerful analytical tool for characterizing viral vectors and assessing their stability under varying process conditions in this 38-minute webinar presented by Hena Divanovic, an Application Scientist specializing in cell and gene therapy process development. Explore the critical role of viral vectors, particularly adeno-associated virus (AAV) and lentiviral vectors (LVV), as delivery vehicles for life-saving cell and gene therapies, and understand how their distinct structural properties lead to different behaviors under environmental stress. Discover how mass photometry overcomes the limitations of existing analytical techniques that are complex, resource-intensive, and limited in resolution and sensitivity for assessing vector integrity and heterogeneity at the single-particle level. Gain valuable insights into vector robustness through stress-testing methodologies that enable identification of process vulnerabilities and support risk mitigation strategies during gene therapy development. Master the application of this innovative approach to characterize viral vectors following stress-testing, providing essential knowledge for optimizing downstream processes and ensuring the safety and efficacy of gene therapy products. Earn 1 PACE credit by registering as a Labroots member and completing the viewing requirements.