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Explore the deadly impact of mosquito-borne diseases throughout history in this 17-minute educational video that examines how these tiny insects may have changed the course of civilization. Discover the compelling evidence suggesting that Alexander the Great, along with other influential historical figures like Pope Sixtus V, Oliver Cromwell, and Charles Leclerc, met their demise through mosquito-transmitted illnesses. Learn about the scientific methods historians and researchers use to investigate these ancient medical mysteries, and understand how diseases carried by mosquitoes have shaped major historical events and the rise and fall of empires. Gain insight into the ongoing battle between humanity and these disease-carrying insects, and appreciate how modern medical knowledge helps us understand the true causes behind some of history's most significant deaths.