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Coursera

Vitamins

via Coursera

Overview

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Vitamins are essential micronutrients that the body cannot make in sufficient quantity on its own, and each has its own biochemical roles and deficiency diseases. This course covers vitamin A and its role in vision and retinoic acid signaling, vitamin D's role in calcium homeostasis – including how parathyroid hormone and calcitonin regulate calcium and phosphate levels and how vitamin D acts inside the cell – and vitamin B12 and folate metabolism, including how folate metabolism connects to the nucleotide synthesis pathways covered in Purine and Pyrimidine Metabolism. Throughout, the course ties each vitamin's biochemistry to the clinical conditions that arise from deficiency or dysregulation, giving you a working knowledge of vitamins that applies directly to nutrition and clinical coursework.

Syllabus

  • Vitamin A: Vision and Retinoic Acid Function
    • This module covers the forms of vitamin A and their central role in the visual cycle, from light detection in rods and cones to the additional functions of retinoic acid.
  • Vitamin D: Calcium Homeostasis and Signaling
    • This module covers the synthesis of vitamin D, the hormonal regulation of calcium homeostasis by PTH and calcitonin, and the intracellular signaling roles of vitamin D and calcium within cells.
  • Vitamin K and Vitamin E
    • This module covers the roles of vitamin K in blood-clotting protein carboxylation and vitamin E as a lipid-soluble antioxidant that protects cell membranes from peroxidation.
  • Vitamin B12 and Folate Metabolism
    • This module covers the metabolic roles of vitamin B12 in propionic acid and methionine pathways and the functions of folate and tetrahydrofolate in nucleotide synthesis, along with the disorders that result from deficiency of either vitamin.

Taught by

Kevin Ahern, PhD

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