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Endocrine Physiology Course

Medicosis Perfectionalis via YouTube

Overview

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Learn comprehensive endocrine physiology through this 16-hour course covering hormones, cell signaling mechanisms, and major endocrine glands. Master cellular receptor types including G-proteins (Gq, Gs, Gi), JAK-STAT pathways, and insulin receptors while exploring genomic versus non-genomic hormone actions. Study the hypothalamus-pituitary axis, examining growth hormone regulation, prolactin control, and posterior pituitary hormones like ADH and oxytocin. Explore thyroid physiology including T3 and T4 synthesis and regulation, alongside calcium homeostasis involving PTH, calcitonin, and vitamin D metabolism. Investigate adrenal gland function covering mineralocorticoids like aldosterone, glucocorticoids including cortisol, and adrenal androgens, plus catecholamine production from the adrenal medulla. Examine pancreatic endocrine function focusing on insulin and glucagon regulation, diabetes mellitus pathophysiology, and somatostatin's inhibitory effects. Delve into reproductive endocrinology covering GnRH, gonadotropins (FSH/LH), testosterone, estrogens, progesterone, and menstrual cycle regulation. Study clinical correlations including growth disorders, diabetes insipidus, SIADH, Cushing syndrome, Addison's disease, congenital adrenal hyperplasia, and various endocrine tumors like prolactinomas and pheochromocytomas.

Syllabus

G-protein (Gq, Gs, Gi), JAK-STAT, RTK, NRTK — Genomic vs Non-Genomic actions — Cell Signaling
Anterior Pituitary Gland - The 10 Commandments of Endocrinology - Endocrine Physiology
Growth Hormone (GH) - Somatotropin - Dwarfism, Gigantism, Acromegaly - Endocrine Physiology
Insulin-like growth factor (IGF-1) - Somatomedin C - GH- Dwarfism, Gigantism, Acromegaly - Endocrine
Prolactin - Prolactinoma - Hyperprolactinemia - Dopamine, TRH - Pathophysiology
Anti-diuretic Hormone (ADH) | Vasopressin | Diabetes Insipidus vs SIADH | Pathophysiology
Oxytocin (OXT) | Milk Let down | Labor contractions | Coitus | Physiology
Thyroid Hormone (T3, T4) | Endocrinology Physiology
Calcium Homeostasis | PTH, Calcitonin & Vitamin D | Endocrine Physiology
Phosphate homeostasis | PTH, Calcitonin, Vitamin D | Endocrine Physiology
PTH, Calcitonin, and 1,25-di(OH)-cholecalciferol (Vitamin D) | Endocrine Physiology
Mineralocorticoids (Aldosterone) - Zona Glomerulosa - Adrenal Cortex - Endocrine Physiology Series
Glucocorticoids (Cortisol, corticosterone)..Corticosteroids of the zona fasiculata, Cushing, Addison
Adrenal Androgens (DHEA, Androstenedione) | Adrenogenital Syndrome | Endocrine Physiology
Congenital Adrenal Hyperplasia (CAH) | 11, 17, and 21-hydroxylase deficiencies Endocrine Physiology
Catecholamines (Epinephrine and Norepinephrine, Dopamine)...Adrenal medulla | Endocrine Physiology
Insulin, Insulinoma & Diabetes Mellitus (DM) | Type 1 vs Type 2 | Endocrine Physiology & Pathology
Glucagon & Glucagonoma - Pancreas - Endocrine Physiology
Somatostatin & Somatostatinoma | The Universal Inhibitor | Endocrine Physiology
All Endocrine Physiology in 25 Minutes | Quick Review | Endocrine Physiology Series
All Metabolism in 20 minutes | Quick Review | Physiology
Overview of Metabolism…Feeding (absorptive) state vs Fasting State (postabsorptive).
GnRH, FSH, LH (Gonadotropins) - Endocrine Physiology
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Reproductive Physiology…An Introduction | Reproductive Physiology
Male Reproductive System - Reproductive Anatomy & Physiology
The Testicles (Seminiferous tubules, Sertoli cells, Leydig cells) | Reproductive Physiology
Androgens (Testosterone, and the Adrenal Androgens) | Reproductive Physiology Series
Dihydrotestosterone (DHT) | More Potent than Testosterone | Reproductive Physiology
Testosterone vs Dihydrotestosterone (DHT) | Which is more potent? What’s the difference?
The Male Sexual Act, Erection, Ejaculation, Penis (Male Copulatory Organ) | Male Reproductive System
The Female Reproductive System | Ovulation, Menstruation, FSH, LH, Estrogen| Reproductive Physiology
The ovary (ovaries)- Female Gonads (Granulosa cells, Theca Cells, Follicles, Luteal Body) Physiology
The Menstrual Cycle- 3 Phases: Follicular (Proliferative), Secretory (Luteal), Menstrual (Bleeding)
Catecholamines (Epinephrine, No-Epinephrine, Dopamine), Metanephrines, HVA, VMA | Pheochromocytoma
Estrogens (Estradiol, Estriol, Estrone) | E1, E2, E3 | Reproductive Physiology Series
Progesterone | the “Pro-gestation” or “Pro-pregnancy” Female Hormone | Reproductive Physiology
Estrogens and the Liver - Gallstones, Hepatic Adenomas, LDL, HDL, TBG, SHBG, p450
Human Chorionic Gonadotropin (hCG)- Pregnancy test | Reproductive Physiology
Sertoli cell vs. Leydig cell - Reproductive System Physiology
Renin Angiotensin Aldosterone System (RAAS) - Physiology
Cushing Syndrome - Urine Cortisol Level - (24-hour-urine cortisol)- Hypercortisolism -Endocrine Labs
Pro-opio-melano-cortin (POMC), Melanocytes Stimulating Hormone (MSH), Skin Pigmentation - Endocrine
Hyperprolactinemia - Pituitary Adenoma - Pituitary Tumors - Prolactinoma
Physiology - Quick Review - In 90 Minutes Series - Part 1 - Physiology Quick Review

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Medicosis Perfectionalis

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