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Considerations in the Development of Biologics with Dr. Mansoor Khan
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Classroom Contents
NIH Principles of Clinical Pharmacology
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- 1 Introduction to Module 1 with Dr. Craig Thomas
- 2 Introduction to Clinical Pharmacology and Therapeutics - Part 1: Overview of Clinical Pharmacology
- 3 Introduction to Clinical Pharmacology and Therapeutics - Part 2: Pharmacokinetic Concepts
- 4 Introduction to Pharmacology, Drug Development and Clinical Pharmacology with Dr. William D. Figg
- 5 Practical Pharmacology with Dr. Anne Zajicek
- 6 Biochemical Mechanisms for Drug Toxicity with Dr. A. Beasley Green
- 7 Ethics in Pediatric Clinical Pharmacology with Dr. Donna L. Snyder
- 8 Ethics in Adult Clinical Pharmacology with Dr. Ezekiel J. Emanuel
- 9 Introduction to Module 2 with Dr. Anne Zajicek
- 10 Drug Absorption and Bio-availability with Dr. Jan Beumer
- 11 Multicompartmental Pharmacokinetic Modeling with Dr. Scott R. Penzak
- 12 Noncompartmental vs. Compartmental Approaches to Pharmacokinetic Analysis with Dr. Paolo Vicini
- 13 Population Pharmacokinetics with Dr. Robert R. Bies
- 14 Chemical Analysis of Drugs and Metabolites with Dr. Andrew Goey
- 15 Pharmacokinetics/Pharmacodynamics of Protein Drugs with Dr. Jürgen Venitz
- 16 Pharmacokinetics & Pharmacodynamics of Therapeutic Proteins Part 1 of 5 with Dr. Bernd Meibohm
- 17 Pharmacokinetics & Pharmacodynamics of Therapeutic Proteins Part 2 of 5 with Dr. Bernd Meibohm
- 18 Pharmacokinetics & Pharmacodynamics of Therapeutic Proteins Part 3 of 5 with Dr. Bernd Meibohm
- 19 Pharmacokinetics & Pharmacodynamics of Therapeutic Proteins Part 4 of 5 with Dr. Bernd Meibohm
- 20 Pharmacokinetics & Pharmacodynamics of Therapeutic Proteins Part 5 of 5 with Dr. Bernd Meibohm
- 21 Introduction to Module 3 with Dr. Lisa M. Cordes
- 22 Pathways of Drug Metabolism Part 1 of 2 with Dr. Kenneth Thummel
- 23 Pathways of Drug Metabolism Part 2 of 2 with Dr. Deanna Kroetz
- 24 P-Glycoprotein and Drug Transport: Case Study with Jomy George
- 25 Membrane Transport with Dr. Kathy Giacomini
- 26 Drug Transport Across the Blood Brain Barrier with Dr. Sadhana Jackson
- 27 Introduction to Module 4 with Dr. Bruce Waldrop
- 28 Pharmacokinetic Considerations in Patients with Renal Impairment Part 1 of 3 with Dr. Darren Roberts
- 29 Pharmacokinetic Considerations in Patients with Renal Impairment Part 2 of 3 with Dr. Darren Roberts
- 30 Pharmacokinetic Considerations in Patients with Renal Impairment Part 3 of 3 with Dr. Darren Roberts
- 31 Pharmacokinetics in Patients Requiring Hemodialysis with Dr. Arthur Atkinson
- 32 Pharmacokinetics in Patients Requiring Renal Replacement Therapy Part 2 of 2 with Dr. Gregory Susla
- 33 The Liver and Drugs with Dr. Jürgen Venitz
- 34 Drug Therapy in Pregnant and Nursing Women with Dr. Anne Zajicek
- 35 Developmental and Pediatric Pharmacology with Dr. John N. van den Anker
- 36 Drug Therapy in the Geriatric Population with Dr. Darrell R. Abernethy
- 37 Pharmacokinetics and Obesity with Dr. Manjunath Pai
- 38 Introduction to Module 5 with Dr. Terry Seaton
- 39 Biomarkers of Drug Effects of Dr. Robert Schuck
- 40 Pharmacodynamic and Pharmacokinetic Modeling of Data with Dr. Joga Gobburu
- 41 Disease Progression Models with Dr. Diane Mould
- 42 Role of Pharmacodynamics in Drug Development with Dr. James Doroshow
- 43 Introduction to Module 6 with Dr. William Zamboni
- 44 Drug Discovery with Dr. Edward Sausville
- 45 Quantitative Systems Pharmacology with Dr. D. Lansing Taylor
- 46 Computational Methods of Drug Discovery and Design with Dr. Glen Kellogg
- 47 Combinatorial Drug Screening with Dr. Craig Thomas
- 48 Natural Products with Dr. Barry O'Keefe
- 49 Drug Formulation & Delivery with Dr. Robert Ternik
- 50 Considerations in the Development of Biologics with Dr. Mansoor Khan
- 51 Drug Development in the Pediatric Population with Dr. Anne Zajicek
- 52 Animal Scale Up and First-in-Human Studies with Dr. Jerry Collins
- 53 Dose Selection and Optimization in the Adult Population with Dr. Yaning Wang
- 54 Design of Clinical Drug Development Programs with Dr. Christopher D. Breder
- 55 FDA Approval Considerations with Dr. Paul Kluetz
- 56 Introduction to Module 7 with Dr. Elvin Price
- 57 Pharmacometabolomics: Implications for Clinical Pharmacology with Dr. Richard Weinshilboum
- 58 Pharmacogenomics with Dr. Michael Pacanowski
- 59 Dose Modifications Based on Pharmacogenomics Research with Dr. Howard McLeod
- 60 Clinical Pharmacogenomics Testing with Dr. Mary Relling
- 61 Clinical Drug Interactions with Dr. Sarah Robertson
- 62 Clinical Assessment of Adverse Drug Reactions with Dr. Christopher D. Breder
- 63 Post-Marketing Drug Safety Surveillance with Dr. Peter Waldron
- 64 Quality Assurance for Drug Therapy with Dr. Charles Daniels
- 65 Use of Positron Emission Tomography (PET) in Pharmacokinetics with Dr. Robert Innis
- 66 Enabling Technologies in Drug Formulation with Dr. Ping Gao
- 67 Immunotherapeutics with Dr. James Gulley
- 68 T-Cell Therapies: Principles and Practice with Dr. James Yang
- 69 Introduction to Mass Spectrometry: A Case Study with Dr. Robert Parise
- 70 PK/PD of Protein Drugs: A Case Study with Dr. Jürgen Venitz
- 71 "Victims & Perpetrators" in Therapeutics" Case Study with Dr. Lionel D. Lewis
- 72 Transporter Mediated Drug-Drug Interactions: A Case Study with Dr. Jomy M. George
- 73 PK/PD Modeling Exercise with Dr. Cody J. Peer
- 74 Discussion on Clinical Trial Endpoints with Dr. Barry Goldspiel
- 75 Immunotherapy-Related Adverse Events Case Study with Dr. Lisa M. Cordes
- 76 Vignettes on Population Pharmacokinetic Modeling Part 2 of 2 with Dr. Robert R. Bies
- 77 Vignettes on Population Pharmacokinetic Modeling Part 1 of 2 with Dr. Robert R. Bies
- 78 Compartmental Analysis of Drug Distribution with Dr. Arthur Atkinson
- 79 Drug Transporters in ADME and Drug Action with Dr. Joseph Ware
- 80 P-Glycoprotein and Drug Transport Part 1 of 2 with Dr. Michael Gottesman
- 81 P-Glycoprotein and Drug Transport Part 2 of 2 with Dr. Matthew Hall