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00:01:10 - 00:02:36 Genetic Mechanism of Resistance
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Classroom Contents
MRSA - Methicillin Resistant Staphylococcus Aureus - SuperBug
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- 1 00:00:37 - 00:04:11 Definition and Nomenclature
- 2 00:01:10 - 00:02:36 Genetic Mechanism of Resistance
- 3 00:05:34 - 00:09:50 Molecular Mechanism of Resistance
- 4 00:00:11 - 00:00:37 Significance of MRSA
- 5 00:12:24 - 00:12:47 Initial success in combating bacterial growth
- 6 00:13:31 - 00:14:05 Responsible for strengthening bacterial cell structure
- 7 00:14:21 - 00:15:09 Disrupts protein function and cell wall formation
- 8 00:16:47 - 00:17:54 Ultimately causes bacterial cell to burst
- 9 00:19:18 - 00:21:20 Carbapenemases
- 10 00:21:57 - 00:22:11 By 1960, many bacteria could secrete beta-lactamases
- 11 00:22:29 - 00:23:26 Structural modifications prevented enzyme destruction
- 12 00:24:20-00:24:41 Created beta-lactamase resistant penicillins
- 13 00:26:00-00:26:33 Produced altered protein: Penicillin Binding Protein 2A PBP2A
- 14 00:28:42-00:29:09 Maintained bacterial functionality despite antibiotic exposure
- 15 00:31:58-00:32:09 Almost All Beta-Lactam Antibiotic Resistant Staphylococcus Aureus
