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Finding Disease Phenotypes and Candidate Therapeutics Using Images: Cell Painting
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- 1 Intro
- 2 Large-scale imaging experiments
- 3 Image-based profiling: use images to create signatures of genes, compounds and diseases
- 4 What is image-based profiling via Cell Painting?
- 5 Identify a difference between diseased and healthy cells
- 6 Identifying disease phenotypes by image-based profiling
- 7 Genes cluster based on morphological similarity
- 8 Identifying chemical regulators of genes by virtual screen
- 9 Morphological profiling can predict small molecule mechanism of action
- 10 Can we predict assay readouts for compounds using image data?
- 11 Predicting many cell health assays from Cell Painting
- 12 Cell Painting: Biomedicine problems machine learning problems?
