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De Novo Design of High-Affinity Binders for Bioactive Helical Peptides

De Novo Design of High-Affinity Binders for Bioactive Helical Peptides

Valence Labs via YouTube Direct link

- AF2 Hallucination

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- AF2 Hallucination

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Classroom Contents

De Novo Design of High-Affinity Binders for Bioactive Helical Peptides

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  1. 1 - Intro + Background
  2. 2 - Parametric Design
  3. 3 - RFJoint Inpainting + ProteinMPNN
  4. 4 - AF2 Hallucination
  5. 5 - RFDiffusion
  6. 6 - Partial Diffusion
  7. 7 - Peptide Binders as Diagnostic Tools
  8. 8 - Conclusion
  9. 9 - Q+A

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