Broad Institute Courses

The Genomics 2 Proteins Portal - MPG Primer 2025

Explore the Genomics 2 Proteins Portal through expert insights from the Iqbal Lab, covering essential tools and methods for translating genomic data into protein-level understanding.

• YouTube
• 52 minutes
• Self-Paced
• Free Video

Permutation Enhances the Rigor of Genomics Data Analysis - mcRigor

Discover advanced permutation-based methods scDEED and mcRigor that enhance reliability in single-cell genomics data analysis, improving visualization accuracy and metacell partitioning.

• YouTube
• 1 hour 47 minutes
• Self-Paced
• Free Video

A General-Purpose Biomedical AI Agent - AI Agents for Biomedical Discovery

Discover Biomni, a general-purpose biomedical AI agent that autonomously executes research tasks across gene prioritization, drug discovery, and clinical analysis using LLM reasoning and code execution.

• YouTube
• 1 hour 44 minutes
• Self-Paced
• Free Video

Foundation Models in Biomedicine - From Modeling the Tissue to Modeling All of Biology

Explore foundation models in biomedicine, from tissue-level modeling to comprehensive biological systems for advancing drug discovery through machine learning applications.

• YouTube
• 39 minutes
• Self-Paced
• Free Video

Predicting Small-Molecule Binding Sites Using AlphaFold2 and Leveraging Deep Learning Model Embeddings for Protein Property Prediction

Explore AF2BIND, a novel approach using AlphaFold2 features to predict protein binding sites for drug discovery, plus deep learning embeddings for protein design.

• YouTube
• 1 hour 51 minutes
• Self-Paced
• Free Video

Mendelian Randomization - MPG Primer 2025

Discover how genetic variants serve as natural experiments to infer causal relationships between traits and diseases in this genetics primer on Mendelian randomization methods.

• YouTube
• 52 minutes
• Self-Paced
• Free Video

Obesity ML Competition - Data Experiment Overview - Lecture 3, Part A

Explore experimental data design for predicting CRISPR gene perturbation effects on adipocyte cell fate in obesity research using machine learning techniques.

• YouTube
• 11 minutes
• Self-Paced
• Free Video

Obesity ML Competition - Measuring Gene Expression in Cells - Lecture 2, Part B

Explore cutting-edge techniques for measuring gene expression in cells, focusing on CRISPR/Cas9 perturbations and adipocyte biology for obesity research applications.

• YouTube
• 16 minutes
• Self-Paced
• Free Video

Obesity ML Competition - Gene Expression Programs Technology - Lecture 2, Part A

Explore gene expression programs and CRISPR/Cas9 technology for predicting adipocyte fate in obesity research through machine learning techniques.

• YouTube
• 12 minutes
• Self-Paced
• Free Video

Introduction to R for Data Analysis - 2024

Gain insights into R programming fundamentals for medical and population genetics data analysis through expert-led discussions of essential concepts and practical applications.

• YouTube
• 50 minutes
• Self-Paced
• Free Video

Modeling Genotype to Phenotype: A Search for Natural Objects of Selection

Explore evolutionary dynamics through metabolism as a genotype-phenotype map, examining how collective modes in phenotype space serve as natural selection objects rather than individual genes.

• YouTube
• 1 hour 42 minutes
• Self-Paced
• Free Video

Connecting the Dots: Biology at Scale in the Age of AI - Session 1

Explore cutting-edge AI applications in biological prediction models, featuring expert discussions on bridging computational and biological approaches to advance scientific discovery.

• YouTube
• 1 hour 49 minutes
• Self-Paced
• Free Video

A Comparative Genomics Strategy to Discover Mechanisms of Cellular Resilience - 2024

Explore comparative genomics approaches for understanding cellular resilience mechanisms through expert insights into human genetics, biostatistics, and computational genomics research.

• YouTube
• 51 minutes
• Self-Paced
• Free Video

Measuring Gene Expression in T Cells for Cancer Immunotherapy - Lecture 2

Discover how gene expression measurement techniques in cells contribute to understanding and enhancing T-cell based cancer immunotherapy approaches through advanced sequencing technologies.

• YouTube
• 23 minutes
• Self-Paced
• Free Video

Cancer Immunotherapy Data Science Challenge: Data Overview - Lecture 3B

Dive into single-cell sequencing data analysis and machine learning applications for enhancing T-cell effectiveness in cancer immunotherapy through genetic modification strategies.

• YouTube
• 16 minutes
• Self-Paced
• Free Video