Broad Institute Courses

Searching through Materials: Generate, Emulate, Simulate

Explore Max Welling's insights on materials research through generation, emulation, and simulation techniques in this MIT-Harvard colloquium on machine learning applications in biomedical research.

• YouTube
• 1 hour 2 minutes
• On-Demand
• Free Video

Ultra-Secure Computing with Homomorphic Encryption for Genome Privacy

Discover how homomorphic encryption enables ultra-secure genomic computations on encrypted data without exposing sensitive information, addressing privacy concerns in large-scale biobanks.

• YouTube
• 36 minutes
• On-Demand
• Free Video

Introduction to the Obesity Machine Learning Competition - Tackling Metabolic Diseases

Discover how gene perturbations affect adipocytes in this machine learning challenge tackling obesity and metabolic diseases using CRISPR/Cas9 data.

• YouTube
• 12 minutes
• On-Demand
• Free Video

A General-Purpose Biomedical AI Agent - AI Agents for Biomedical Discovery

Discover Biomni, a general-purpose biomedical AI agent that autonomously executes research tasks across gene prioritization, drug discovery, and clinical analysis using LLM reasoning and code execution.

• YouTube
• 1 hour 44 minutes
• On-Demand
• Free Video

Foundation Models in Biomedicine - From Modeling the Tissue to Modeling All of Biology

Explore foundation models in biomedicine, from tissue-level modeling to comprehensive biological systems for advancing drug discovery through machine learning applications.

• YouTube
• 39 minutes
• On-Demand
• Free Video

Predicting Small-Molecule Binding Sites Using AlphaFold2 and Leveraging Deep Learning Model Embeddings for Protein Property Prediction

Explore AF2BIND, a novel approach using AlphaFold2 features to predict protein binding sites for drug discovery, plus deep learning embeddings for protein design.

• YouTube
• 1 hour 51 minutes
• On-Demand
• Free Video

Mendelian Randomization - MPG Primer 2025

Discover how genetic variants serve as natural experiments to infer causal relationships between traits and diseases in this genetics primer on Mendelian randomization methods.

• YouTube
• 52 minutes
• On-Demand
• Free Video

Obesity ML Competition - Data Experiment Overview - Lecture 3, Part A

Explore experimental data design for predicting CRISPR gene perturbation effects on adipocyte cell fate in obesity research using machine learning techniques.

• YouTube
• 11 minutes
• On-Demand
• Free Video

Obesity ML Competition - Measuring Gene Expression in Cells - Lecture 2, Part B

Explore cutting-edge techniques for measuring gene expression in cells, focusing on CRISPR/Cas9 perturbations and adipocyte biology for obesity research applications.

• YouTube
• 16 minutes
• On-Demand
• Free Video

Obesity ML Competition - Gene Expression Programs Technology - Lecture 2, Part A

Explore gene expression programs and CRISPR/Cas9 technology for predicting adipocyte fate in obesity research through machine learning techniques.

• YouTube
• 12 minutes
• On-Demand
• Free Video

Entering the Genomic Medicine Era - How Technology, Data, and Biology Can Improve Healthcare Throughout Our Lives

Explore how genomic medicine and precision healthcare technologies could transform medical care throughout your life with insights from Broad Institute scientist Niall Lennon.

• YouTube
• 1 hour 16 minutes
• On-Demand
• Free Video

The Genomics 2 Proteins Portal - MPG Primer 2025

Explore the Genomics 2 Proteins Portal through expert insights from the Iqbal Lab, covering essential tools and methods for translating genomic data into protein-level understanding.

• YouTube
• 52 minutes
• On-Demand
• Free Video

Permutation Enhances the Rigor of Genomics Data Analysis - mcRigor

Discover advanced permutation-based methods scDEED and mcRigor that enhance reliability in single-cell genomics data analysis, improving visualization accuracy and metacell partitioning.

• YouTube
• 1 hour 47 minutes
• On-Demand
• Free Video

Beyond Prediction - Causal Validity in ML-Driven Drug Discovery and Health Monitoring

Explore causal validity in machine learning for drug discovery and health monitoring, moving beyond prediction to establish causality in therapeutic target discovery and glucose dynamics modeling.

• YouTube
• 1 hour 2 minutes
• On-Demand
• Free Video

Programmatic Design and Editing of Cis-Regulatory Elements Using Deep Learning - Inferring Transcription Factor Binding from Chromatin Accessibility

Explore cutting-edge deep learning methods for designing genomic edits and predicting transcription factor binding in regulatory genomics research.

• YouTube
• 1 hour 42 minutes
• On-Demand
• Free Video