Broad Institute Courses

Structural Variation in Human Genomes - MPG Primer 2024

Explore structural variations in human genomes, their impact on genetics, and cutting-edge analysis techniques with experts from the Broad Institute.

• YouTube
• 45 minutes
• Self-Paced
• Free Video

SPLASH: Ultraefficient Statistics-First Analysis of Raw Sequencing Data - Lecture

Explore SPLASH, a revolutionary statistics-first approach for genomic analysis without reference genomes. Discover its efficiency in detecting diverse genetic mechanisms and its potential to transform genomic research and discovery.

• YouTube
• 1 hour 44 minutes
• Self-Paced
• Free Video

Models, Inference and Algorithms - Lightning Talks

Explore cutting-edge research in models, inference, and algorithms through lightning talks by five postdoctoral researchers at the Broad Institute of MIT and Harvard.

• YouTube
• 1 hour 26 minutes
• Self-Paced
• Free Video

MPG Primer: Understanding Single Cell ATAC-Seq Data Analysis (2024)

Explore single-cell ATAC-seq data analysis, covering key concepts, workflow, quality control, and downstream analysis techniques for epigenomic profiling at cellular resolution.

• YouTube
• 45 minutes
• Self-Paced
• Free Video

Chrono-energetics - Linking Circadian Metabolism to Islet Replacement Therapeutics

Explore chrono-energetics and its impact on islet replacement therapies in diabetes treatment with Juan Alvarez-Dominguez's insightful presentation.

• YouTube
• 52 minutes
• Self-Paced
• Free Video

PheWAS and UKBB in Medical and Population Genetics - 2024 MPG Primer

Explore phenome-wide association studies (PheWAS) and UK Biobank (UKBB) applications in medical and population genetics, focusing on complex trait analysis and large-scale genomic data.

• YouTube
• 47 minutes
• Self-Paced
• Free Video

Unsupervised Viral Antibody Escape Prediction for Future-Proof Vaccines - Lecture

Explore unsupervised viral antibody escape prediction for future-proof vaccines. Learn about EVEscape model integrating fitness predictions, structure-based features, and biochemical distances to quantify viral escape potential at scale.

• YouTube
• 1 hour 46 minutes
• Self-Paced
• Free Video

Data Thinning to Avoid Double Dipping in Statistical Analysis - Lecture 1

Explore data thinning techniques to prevent double dipping in statistical analysis, with applications in single-cell RNA sequencing and unsupervised learning problems.

• YouTube
• 1 hour 32 minutes
• Self-Paced
• Free Video

A Practical Guide to Bulk RNA-seq, Including Guidelines for eQTL Analysis - 2024

Explore practical bulk RNA-seq techniques and eQTL analysis guidelines in this comprehensive guide for medical and population genetics researchers.

• YouTube
• 45 minutes
• Self-Paced
• Free Video

Machine Learning in the Optimization and Discovery Loop

Explore machine learning's role in optimization and discovery with Andreas Krause. Gain insights into biomedical applications and foundational ML advances in this joint colloquium series.

• YouTube
• 1 hour
• Self-Paced
• Free Video

Biomolecular Condensates: New Insights into Regulation and Dysregulation of Cellular Compartments

Explore biomolecular condensates and their role in cellular compartment regulation with Professor Richard Young's seminar on cutting-edge chemical biology research.

• YouTube
• 1 hour 7 minutes
• Self-Paced
• Free Video

MPG Primer: Rare Variant Interpretation - 2024

Explore rare variant interpretation in genetics, covering basic principles, analysis methods, and implications for understanding human diseases and populations.

• YouTube
• 35 minutes
• Self-Paced
• Free Video

Patient Engagement in Genomic Research: Using Social Media to Create a Community - 2024

Explore patient engagement in genomic research through social media, building communities for enhanced collaboration and participation.

• YouTube
• 49 minutes
• Self-Paced
• Free Video

Diffusion Models Towards High-Dimensional Generative Optimization

Explore diffusion models for high-dimensional generative optimization in AI, focusing on biomedical applications and machine learning advancements.

• YouTube
• 1 hour 2 minutes
• Self-Paced
• Free Video

Biomedical Research, Health Equity, and the NIH - Equity in Biomedicine Seminar Series

Explore NIMHD's efforts to address health disparities, improve minority health, and reduce inequities. Learn about integrating social, environmental, and genomic data for achieving health equity.

• YouTube
• 1 hour
• Self-Paced
• Free Video