Broad Institute Courses

MPG Primer: Introduction to Fine-Mapping - 2023

Explore fine-mapping techniques in genetics, covering basic principles, statistical methods, and applications in identifying causal variants for complex traits and diseases.

• YouTube
• 50 minutes
• Self-Paced
• Free Video

Engineering Selective Covalent Ligands for Diverse Applications in Biology

Explore the design and application of covalent binding small molecule probes for enzyme monitoring, with focus on cancer and infectious disease imaging and therapy targets.

• YouTube
• 1 hour 1 minute
• Self-Paced
• Free Video

Modeling Rare Variation and Calculating Genetic Constraint - MPG Primer 2023

Explore genetic constraint calculation and rare variation modeling techniques for understanding human population genetics and disease mechanisms.

• YouTube
• 50 minutes
• Self-Paced
• Free Video

Seurat v5: Cross-Modality Mapping and Large-Scale Clustering of Single-Cell Data

Explore advanced techniques for integrating and analyzing single-cell data across modalities using Seurat v5, including bridge integration and atomic sketching for improved scalability and clustering.

• YouTube
• 49 minutes
• Self-Paced
• Free Video

Building a Mind for Cancer

Explore innovative approaches to understanding cancer through AI and machine learning with Trey Ideker's insightful presentation on building a computational mind for cancer research.

• YouTube
• 57 minutes
• Self-Paced
• Free Video

Greater Genetic Diversity is Needed in Human Pluripotent Stem Cell Models - 2023

Explore genetic diversity in human pluripotent stem cell models and its importance for medical research. Learn about complex trait genetics and cutting-edge DNA sequencing methods.

• YouTube
• 42 minutes
• Self-Paced
• Free Video

Mono- and Bi-valent Allele Impact in Medical and Population Genetics - 2023 Primer

Explore mono- and bi-valent allele impact in genetics, focusing on population bottlenecks, disease-causing variants, and heterozygous effects. Gain insights from Finland research project.

• YouTube
• 36 minutes
• Self-Paced
• Free Video

Foundation Models for Therapeutic Design and Treatment Prediction

Explore foundation models for therapeutic design and treatment prediction, focusing on novel insights in biomedical research and machine learning advancements.

• YouTube
• 1 hour 3 minutes
• Self-Paced
• Free Video

From Genome Editing to Programmable Medicine - Broad Discovery Series

Explore the evolution of genome editing and programmable medicine with CRISPR pioneer Feng Zhang and his lab members, discussing advancements and future potential in this field.

• YouTube
• 1 hour 9 minutes
• Self-Paced
• Free Video

Ladders to Cures Symposium 2023 - Advances in Rare Disease Research and Therapies

Explore cutting-edge research and developments in rare disease therapies through expert talks on genetics, drug development, biomarkers, and patient-centric approaches.

• YouTube
• 6 hours 57 minutes
• Self-Paced
• Free Video

Generative AI for Modeling Single-Cell Responses

Explore generative AI applications in single-cell response modeling, covering data integration, representation learning, and multiomics analysis for biomedical insights.

• YouTube
• 1 hour 2 minutes
• Self-Paced
• Free Video

Sparsity, Epistasis, and Models of Fitness Functions - Leveraging Interactions in Protein Function Prediction

Explore sparsity in epistatic interactions to enhance fitness function modeling. Learn about Walsh-Hadamard transform, Graph Fourier transforms, and Epistatic Net for improved protein function prediction.

• YouTube
• 1 hour 37 minutes
• Self-Paced
• Free Video

Contrastive Models for Case-Control Changes in Sequencing - Models, Inference and Algorithms

Explore contrastive latent variable models for analyzing differential expression in sequencing data, enhancing case-control comparisons in transcriptomics with novel approaches to capture condition-specific variations.

• YouTube
• 1 hour 8 minutes
• Self-Paced
• Free Video

Harmonization of Deeply Sequenced Genomes - MPG Primer 2023

Explore genome harmonization techniques for deeply sequenced data, covering quality control, structural variants, and PCA analysis using cloud computing.

• YouTube
• 37 minutes
• Self-Paced
• Free Video

MPG Primer: suSIEx - Medical and Population Genetics 2023

Explore suSIEx, a cutting-edge method for analyzing genetic data in medical and population genetics. Learn its principles, applications, and potential impact on understanding complex traits and diseases.

• YouTube
• 39 minutes
• Self-Paced
• Free Video