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Explore how optimization techniques are revolutionizing various industries in the age of AI and cloud computing through this insightful conference talk. Delve into novel optimization problems emerging in fields such as live streaming, virtual machine technology, digital human creation, physics engines, and AI-chip design. Gain a deeper understanding of how these cutting-edge challenges are mathematically represented and analyzed. Examine the complexities involved and recent advancements in addressing these issues from optimization and operations research perspectives. Discover the practical applications of optimization in solving real-world problems that have yet to be extensively studied in academic circles.