Explore WebAssembly's potential for efficient and secure computation in cloud services and edge computing in this 26-minute conference talk. Gain insights from a systems programmer's perspective on WebAssembly's applications beyond web browsers. Discover how WebAssembly can abstract run-time into infrastructure for cloud services and securely move code from cloud to edge in IoT scenarios. Learn about WebAssembly's role in implementing reactive principles like efficient execution, failure acceptance, space-time decoupling, and rapid code adaptation. Understand the technology's potential to revolutionize IoT computation and provide a competitive advantage in product design. Conclude with valuable observations, advice, and a discussion of unsolved challenges in this emerging field.