Nuclear Receptors with Transcription Factor Activity and Signaling Co-Receptors

Explore the intricate world of nuclear receptor families and their transcription factor activities in this 25-minute lecture from NPTEL-NOC IITM. Delve into the mechanisms of soluble nuclear receptors, understanding how these important cellular components function as transcription factors to regulate gene expression. Learn about the activation processes of nuclear receptors and discover the crucial role of signaling co-receptors in cellular communication pathways. Examine the structural and functional characteristics that distinguish different nuclear receptor families and understand how they respond to various ligands to initiate downstream signaling cascades. Gain insights into the molecular mechanisms that govern receptor activation and the cooperative interactions between primary receptors and their co-receptor partners in cellular signaling networks.