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Explore the scientific and curation processes behind the Catalogue Of Somatic Mutations In Cancer (COSMIC) database in this 40-minute webinar presented by Ellen Wiedemann and Kyle Nilson, PhD. Discover how the Cancer Gene Census (CGC) catalogues genes with causal impact in human cancer, characterizing them as tumor suppressors, oncogenes, or fusion genes while organizing them into evidence-based tiers. Learn about the criteria used to evaluate genes for CGC inclusion and understand the structured information captured within both the CGC and Cancer Mutation Census (CMC) modules. Examine how the CMC classifies coding variants according to their computed pathogenicity to prioritize mutations with proven functional or clinical relevance. Gain insights into real-world applications of these databases across research and clinical oncology contexts, supporting faster interpretation and decision-making in cancer genomics. The webinar offers PACE credits for registered participants and provides comprehensive coverage of COSMIC's role in advancing cancer research and clinical practice.
