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Join a 36-minute webinar led by Dr. Rebecca Moschall, a Scientist at Thermo Fisher GeneArt, exploring a high-throughput semi-automated platform for monoclonal antibody synthesis. Discover how to integrate DNA normalization, transfection, antibody purification, and buffer exchange within a Manufacturing Execution System (MES) to ensure comprehensive traceability. Learn strategies for mitigating late-stage failures through early detection using automated small-scale synthesis, understand how sequence optimization enhances antibody yields from mammalian cell expression, and explore the importance of scale-up consistency in downstream development. Drawing from her extensive background in protein chemistry and biopharmaceutical product testing, Dr. Moschall demonstrates how this platform achieves excellent inter and intra-batch reproducibility, making it particularly suitable for training machine learning algorithms to predict desirable antibody features. Gain insights into this streamlined approach that addresses the growing demand for monoclonal antibodies in therapeutic and diagnostic applications.
