Understanding Epigenetic Mechanisms Through the Engineering of Synthetic Chromatin

Explore the fascinating world of epigenetic mechanisms through a 30-minute conference talk on engineering synthetic chromosomes. Delve into the interdisciplinary aspects of chromatin organization and gene regulation as presented by Ramesh Yelagandula at the International Centre for Theoretical Sciences. Gain insights into how chromatin, a long polymer containing the genetic code, is arranged in 4D space and time, and how its epigenetic state and 3D organization influence gene regulation. Learn about recent advances in genomics, high-resolution microscopy, and single-cell measurements that have revolutionized our understanding of chromatin's complex organization. Discover how this talk contributes to the broader discussion on integrating diverse information from multiple disciplines to comprehend the principles behind chromatin organization and gene regulation.