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Explore physical destruction of GPUs as an innovative defense mechanism against key extraction and supply chain attacks in this 18-minute conference talk. Learn how industrial detonators integrated into modified heatsinks can serve as a security measure, comparing this approach to traditional zeroization techniques and PyroMEMS nanothermite solutions. Examine the practical considerations of balancing effectiveness, cost, and reliability when implementing such extreme security measures in high-stakes environments. Discover the technical aspects of GPU detonation systems and their potential applications in protecting sensitive cryptographic materials and preventing unauthorized access to critical hardware components.