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Emergent Oscillations During Cellular Directional Decision-Making on Junctions

INI Seminar Room 2 via YouTube

Overview

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Explore a scientific lecture where Professor Nir Gov from the Weizmann Institute of Science discusses the fascinating phenomenon of cellular movement decision-making at junctions. Learn about a theoretical model explaining how cells navigate one-dimensional paths and make directional choices at Y-junctions through spontaneous oscillatory behavior. Discover how cellular polarization alternates between competing protrusions during migration, and understand how these oscillations, though affected by cellular noise, significantly influence junction crossing time. Examine experimental evidence supporting these theoretical predictions through studies of both noncancerous endothelial and cancerous glioma cells moving on patterned networks with adhesive lanes and junctions. Gain insights into new statistical physics applications in living matter, particularly focusing on non-equilibrium states under adaptive control.

Syllabus

Date: 21st Sept 2023 - 11:00 to

Taught by

INI Seminar Room 2

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