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Learn about the latest developments in SPECT imaging for alpha radiopharmaceutical therapy in this comprehensive 48-minute lecture delivered by Dr. Yong Du, Associate Professor of Radiology at Johns Hopkins University. Explore fundamental concepts of radiopharmaceutical therapy (RPT), comparing beta and alpha RPTs, and understand the importance of dosimetry in treatment planning. Dive deep into quantitative SPECT activity estimation, analyze the differences between SPECT and PET imaging modalities, and examine the specific challenges associated with imaging alpha-emitters. Discover innovative solutions for alpha emitter imaging, including insights from animal studies with Ac-225 and patient SPECT/CT imaging using Fr-221 and Bi-213. The lecture concludes with an overview of new alpha SPECT systems and their potential impact on molecular imaging and therapy.
