SARS-CoV-2 Interactions with the Host Innate Immune Response and the Ubiquitin System

Explore the intricate interactions between SARS-CoV-2 and the host innate immune response in this 35-minute webinar presented by Dr. Ricardo Rajsbaum, Associate Professor and Director of the Center for Virus-Host-Innate Immunity at Rutgers New Jersey Medical School. Delve into the mechanisms used by SARS-CoV-2 to evade the antiviral innate immune response, with a particular focus on its interactions with the host ubiquitin system. Learn about the host's recognition of SARS-CoV-2 infection, the resulting signaling cascades, and the production of cytokines and type-I Interferons. Understand how the virus antagonizes both interferon induction and signaling to escape detection. Gain insights into the regulation of the interferon system through various molecular processes, including the ubiquitin system, and how this knowledge contributes to our understanding of SARS-CoV-2 pathogenesis.