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Explore how Kubernetes, Prometheus, and Helm are utilized to run complex bioinformatics tools like Kraken at scale in this conference talk. Discover the challenges of applying the taxonomic sequence classification tool Kraken, known for its intense resource requirements, in a scalable manner. Learn about Day Zero Diagnostics' approach to supporting rapid profiling of pathogenic bacteria using modern tooling and infrastructure. Gain insights into the growing intersection of specialized academic software and its non-academic applications at scale. Delve into the complexities of managing research-oriented bioinformatics tools in a cloud-native environment and understand how containerization and orchestration technologies are revolutionizing the field of bioinformatics.