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Explore the challenges and solutions for reliable Remote Procedure Calls (RPCs) in hybrid cloud environments through this informative conference talk. Delve into the complexities of latency-sensitive and business-critical workloads when faced with various failure modes in hybrid cloud L3 networks. Examine a real-world case study demonstrating how to enhance end-to-end reliability for SaaS and microservice workloads by strengthening L7 RPC protocols like gRPC. Learn about a benchmark framework used to evaluate the effectiveness of L7 algorithms against different L3 failure conditions, including strategies to minimize RPC timeouts over multiplexed transport during sustained packet loss scenarios. Gain valuable insights from Google Inc. experts Wenbo Zhu and Vinod Lasrado on implementing robust RPC systems in hybrid cloud architectures.