Redefining HIV Persistence - The Role of Monocytes and Macrophages as a Latent Reservoir

Explore the critical role of monocytes and macrophages as latent HIV reservoirs in this comprehensive medical lecture by Dr. Rebecca Veenhuis from Johns Hopkins Medicine. Delve into cutting-edge research that redefines our understanding of HIV persistence beyond traditional T-cell reservoirs, examining how these immune cells contribute to viral latency and complicate cure strategies. Learn about the latest findings in neurological HIV research, including the mechanisms by which monocytes and macrophages harbor dormant virus, their impact on HIV pathogenesis, and the implications for developing effective therapeutic interventions. Gain insights into advanced laboratory techniques used to study these cellular reservoirs, understand the challenges they present for HIV eradication efforts, and discover emerging approaches to target these persistent viral sanctuaries. This presentation provides essential knowledge for researchers, clinicians, and students working in HIV/AIDS research, immunology, and infectious disease medicine.