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iSNP - An Advanced Computational Pipeline for Stratifying Patients in Complex Diseases

Imperial College London via YouTube

Overview

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Explore an advanced computational pipeline designed to revolutionize patient stratification in complex diseases through the integrated Single Nucleotide Polymorphism network platform (iSNP). Learn how this precision medicine pipeline elucidates the mechanisms by which SNPs disrupt cellular regulatory networks and contribute to disease development through their combinatorial effects. Discover the computational methodologies used to analyze genetic variations and their impact on regulatory pathways, understand how SNP interactions can be mapped to disease pathogenesis, and examine the practical applications of this pipeline in clinical settings for personalized medicine approaches. Gain insights into the technical architecture of iSNP, its data processing capabilities, and how it enables researchers and clinicians to better understand the complex genetic underpinnings of diseases by analyzing the network-level effects of genetic variations rather than individual SNP impacts.

Syllabus

RCS Day 2025: iSNP: An advanced computational pipeline for stratifying patients in complex diseases

Taught by

Imperial College London

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