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Explore the architecture and development of PTero, a workflow management system designed for large-scale genomic sequence data analysis, in this conference talk from Strange Loop. Discover how PTero utilizes petri nets to represent both directed acyclic graphs and finite state machines, enabling efficient handling of complex workflows. Learn about the system's restful service architecture, which allows for horizontal scaling and resilience against node failures. Gain insights into PTero's deployment at the McDonnell Genome Institute, where it has orchestrated over 600,000 workflows with more than 8 million combined tasks since 2013. Understand the challenges of managing highly parallel computational workflows for genomic data analysis and how PTero addresses these issues through its innovative design and implementation.