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Explore the critical biosecurity challenges and solutions for DNA data storage technology in this 20-minute conference presentation from the 2025 Storage and Computing with DNA Conference. Learn how storing binary data in DNA requires synthesizing vast numbers of unique oligonucleotide sequences, creating unprecedented biosecurity considerations that differ from traditional biological applications. Understand the dual-use nature of DNA technology, which offers tremendous benefits in healthcare, agriculture, and biomanufacturing while potentially enabling harmful applications like synthesizing dangerous viruses. Discover how the nucleic acid synthesis industry has developed comprehensive biosecurity screening systems since 2010 to assess biological risks and verify legitimate customer uses. Examine the unique economic and policy challenges that DNA data storage presents to existing biosecurity frameworks, and identify practical steps the emerging DNA data storage industry can implement to minimize costs while completely eliminating misuse risks. Gain insights from James Diggans of Twist Bioscience on protecting this revolutionary abiological application of DNA technology while maintaining robust security protocols.
