Principles of Operation of a Cerebellar Learning Circuit - Steve Lisberger

Explore the principles of operation in a cerebellar learning circuit through this 48-minute conference talk by Steve Lisberger from Duke University. Recorded as part of the Timescales of Plasticity and Underlying Mechanisms conference at the Kavli Institute for Theoretical Physics, delve into the neurobiology of learning and the challenge of bridging multiple timescales in associative learning. Examine how the brain associates events separated by varying time intervals, from seconds to weeks, despite known biological mechanisms for synaptic changes typically occurring within milliseconds. Gain insights into the molecular, cellular, and circuit-level mechanisms employed by the brain to support learning across different timescales, complementing the conference's computational focus with an emphasis on biological mechanisms. Discover how this integrated analysis of statistical learning spans phenomena from molecular to behavioral levels, contributing to a comprehensive understanding of brain plasticity and learning processes.