Post Cardiac Arrest Syndrome

This course examines post-cardiac arrest syndrome in children, focusing on brain injury, cerebral physiology, targeted temperature management, and post-resuscitation oxygenation. It reviews pediatric guidelines, research evidence, and unresolved clinical questions.

Syllabus

Intro
Objectives
PCAS in the Pediatric Population
Reasons for death after ROSC post-cardiac arrest
Pathophysiology
Severity of Injury
Whole body ischemia
Post Cardiac Arrest Brain Injury
Cerebral Autoregulation Post-ROSC
Cerebral Perfusion Post-ROSC
Cerebral Oxygen Delivery Post-Cardiac Arrest
Cerebral Edema after Cardiac Arrest • Patients post-arrest with ICP and edema
Post-Cardiac Arrest Brain Injury: Summary
Fever Post-Cardiac Arrest
Targeted Temperature Management (TTM) Protects the Brain
TTM Post Cardiac Arrest
Systematic Reviews of TTM
2010 American Heart Association's Guidelines for Post-Resuscitation Care
Pediatric Post-Cardiac Arrest and TTM
2010 AHA Pediatric TTM Guidelines
THAPCA Study - Out of Hospital Arm
Unanswered Questions
Post-ROSC Oxygenation Targets
Arterial Hyperoxia and In-Hospital Mortality After Resuscitation Post-Cardiac Arrest
Post-ROSC Oxygenation: Neonatal Data
Post-ROSC Oxygenation: Pediatric Data
Post-Cardiac Arrest Oxygenation Status and Outcome
Relationship Between Arterial Partial Oxygen Pressure After Resuscitation From Cardiac Arrest and Mortality in Children