Mechanisms of Immune Evasion by RSV Nonstructural Proteins

Learn about the complex mechanisms of immune evasion employed by respiratory syncytial virus (RSV) in this 30-minute webinar presented by Dr. Daisy Leung, Associate Professor at Washington University School of Medicine. Explore how RSV's nonstructural proteins NS1 and NS2 play crucial roles in viral pathogenesis and immune system evasion. Discover recent breakthrough findings from X-ray crystal structure analyses of these proteins and understand their interactions with host components, including cytosolic pathogen sensors and nuclear transcriptional machinery. Gain valuable insights into potential therapeutic approaches and vaccine development strategies based on targeting these nonstructural proteins, particularly relevant for protecting vulnerable populations such as young children, elderly, and immunocompromised individuals from this significant respiratory pathogen.