Explore the intricate relationship between large-scale ocean circulation and climate in this comprehensive lecture on interannual climate variability. Delve into the complex dynamics of ocean-atmosphere interactions and their impact on global climate patterns. Learn about the key processes driving interannual climate fluctuations, such as El Niño-Southern Oscillation (ENSO) and other oceanic phenomena. Gain insights into the latest research and modeling techniques used to understand and predict these climate variations. Suitable for students and researchers interested in oceanography, climatology, and atmospheric sciences, this lecture provides a solid foundation for understanding the crucial role of ocean circulation in shaping our planet's climate system.