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Explore the critical challenges and opportunities in democratizing precision health through genomics in this 23-minute keynote presentation by Dr. Carlos D. Bustamante, PhD. Examine how the explosion of genetic information over the past 20 years has created significant disparities, with most genomic resources focused on northern European communities while underrepresented populations face the greatest burden of chronic disease. Learn about the potential of leveraging data from over 30 million people genotyped by direct-to-consumer companies and large biobank efforts to democratize access to medical interventions and improve patient outcomes. Discover a novel geno-pheno platform that integrates heterogeneous data sources and applies machine learning to common chronic disease conditions. Analyze how the SARS-CoV-2 pandemic has differentially impacted populations of varied race, ethnicity, and socioeconomic status through groundbreaking research that sequenced viral and host genomes from nasopharyngeal swab residuals. Understand the over-representation of individuals with Oceanian and Indigenous American ancestry in SARS-CoV-2 positive populations and how multi-omic pandemic tracking reveals distinct epidemiologic, genetic, and biological associations for high-risk groups. Gain insights into the future of precision medicine through clinical-grade biobanking, research and clinical genomics, paired with advanced ancestry and genome annotation algorithms to better understand the genetic architecture of underserved populations. Explore emerging research on post-infectious acute syndromes, including neuropsychiatric components such as long-COVID and associated disorders, and their implications for the next generation of precision medicine studies.
