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Attend a keynote webinar exploring the revolutionary application of nanovial technology for discovering rare T cell receptors in biomedical research. Learn from Dr. Dino Di Carlo, the Armond and Elena Hairapetian Professor of Bioengineering at UCLA and serial entrepreneur, as he presents cutting-edge research on using nanovials as an accessible platform for single-cell functional screening with standard laboratory instrumentation like flow cytometers and microfluidic single-cell sequencing platforms. Discover how each cell and its secreted products are captured in nanovials for analysis and sorting using widely available fluorescence activated cell sorters. Explore the platform's proven applications in monoclonal antibody discovery before diving deep into recent work using nanovials for T cell selection based on cytokine secretion and downstream T cell receptor (TCR) sequencing. Understand how nanovials enable selective binding, functional characterization of cytokine and effector molecule secretion, followed by T cell sorting for downstream sequencing of TCR alpha and beta chains with functional annotation. Examine how this "lab on a particle" approach can assay both binding and cellular function for millions of cells using standard equipment, accelerating the discovery of monoclonal antibodies, cancer-specific TCRs, and TCRs against metabolites presented by unconventional major histocompatibility complex (MHC)-like molecules with high accuracy. Participate in a live Q&A session to engage directly with the presenter and gain insights into how this technology promises to transform therapeutic antibody discovery and improve T cell therapies. Earn PACE credits by registering as a Labroots member and completing the viewing requirements before the March 20, 2026 expiration date.
