Predicting New Drug Phenotype by Simulating Off Target Effects

Watch this 34-minute conference talk exploring computational methods for predicting drug phenotypes through simulation of off-target effects. Learn how network-based approaches can forecast drug synergistic effects by analyzing downstream protein-protein interactions and gain insights into mechanistic understanding of drug efficacy and safety. Discover the PathFX computational framework that provides regulatory-relevant insights for therapeutic development and explore applications in identifying novel therapeutic targets for neurological diseases including amyotrophic lateral sclerosis using real-world data analysis.