Introduction to Hereditary Sarcoma and Genetic Counselling for Sarcoma - Ambry Genetics

This webinar provides a clinical and genetic overview of hereditary sarcoma, covering major sarcoma subtypes, associated hereditary syndromes, genetic diagnosis, counseling issues, and management practices.

Syllabus

Intro
Objectives
Sarcoma Overview
Li-Fraumeni Syndrome Testing Criteria
Sarcoma in LFS
Li-Fraumeni Syndrome • Medical Management can include
Surveillance: Toronto Protocol for LFS
Survival of TP53 mutation carriers in surveillance and nonsurveillance groups
Counseling and Testing issues in LFS
Family with Li Fraumeni-like syndrome
Familial Adenomatous Polyposis Classic FAP
FAP Management
Desmoid in FAP
Retinoblastoma Monitoring: Secondary
Leiomyosarcoma in Hereditary Rb
Gastrointestinal Stromal Tumor (GIST)
Neurofibromatosis Type
Familial GIST: Germline KIT mutation
Hereditary GIST Management
SDH-deficient GIST: Germline SDHA
Rare Inherited Sarcoma Predisposition
Summary Clinical Approach
Resources