Overview
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Learn how laboratories can implement a transformative decentralized comprehensive genomic profiling (CGP) solution through this 40-minute webinar presented by Pierluigi Iapicca, Senior Subject Matter Expert at SOPHiA GENETICS, and Dr. Kojo Elenitoba-Johnson, Chair of the Department of Pathology and Laboratory Medicine at Memorial Sloan Kettering Cancer Center. Explore MSK-IMPACT® powered with SOPHiA DDM™, a groundbreaking collaboration between Memorial Sloan Kettering Cancer Center and SOPHiA GENETICS that brings world-class genomic profiling capabilities to laboratories worldwide. Discover how this solution applies the same core technology principles behind MSK-ACCESS® powered with SOPHiA DDM™ to FFPE tissue samples using a matched tumor-normal approach that enhances somatic mutation detection while filtering out germline variants and reducing biological false positives. Understand how the platform identifies clonal hematopoietic variants (CHIP) to reveal mutations of true somatic origin and delivers high concordance with single-site MSK-IMPACT® results across SNVs, indels, TMB, MSI, and copy number alterations. Examine how matched tumor-normal sequencing improves somatic detection and interpretation in decentralized CGP settings, and learn how laboratories can implement MSK-level CGP with high biomarker concordance. Gain insights into how this scalable, cloud-based platform supports equitable access to precision oncology by combining MSK's clinical expertise with SOPHiA GENETICS' technological strength in an end-to-end application that improves interpretation, enhances accuracy, and expands access to comprehensive genomic profiling for oncology care.
Syllabus
Insights with Impact: Empowering Laboratories with a Decentralized MSK Solution for CGP
Taught by
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