Explore five key lessons in de Sitter quantum gravity in this informative physics talk presented by Jordan Cotler from Harvard University. Delve into the significant progress made in de Sitter quantum gravity and holography over the past five years through a pedagogical review of important developments. Learn about the computation of de Sitter S-matrix elements, the non-perturbative Hilbert space of de Sitter quantum gravity, the sum over de Sitter spacetime topologies, complexities with the de Sitter path integral measure, and de Sitter holographic dualities. Discover potential directions for future research in this field as highlighted throughout the presentation.