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Join a comprehensive colloquium lecture exploring strategies to combat drug-resistant tuberculosis, delivered by Professor Valakunja Nagaraja from the Indian Institute of Science, Bengaluru. Examine the global health crisis of tuberculosis, which adds millions of new cases and claims two million lives annually, with special focus on the emerging challenge of multiple and total drug-resistant strains of Mycobacterium tuberculosis. Discover various worldwide efforts to fight the disease, including detailed research approaches combining genetics, biophysics, molecular and cell biology to investigate essential proteins crucial for mycobacterial survival. Learn about the development of targeted inhibitors and knock-down strains designed to disrupt bacterial growth and cellular function, revealing new insights into the pathogen's mechanisms and opening doors to novel intervention strategies.