How the Krebs Cycle Powers Life and Death – With Nick Lane

This talk explains the Krebs cycle as a central series of reactions in cellular respiration, including its efficiency and reverse form. It connects the cycle to the origin of life, photosynthesis, mitochondria, cancer, and disease.

Syllabus

Metabolic pathways of life
The Krebs cycle - simplified
How cells respire
What cancer taught us about the Krebs cycle
How is the Krebs cycle efficient?
The reverse Krebs cycle
Margaret Dayhoff - the founder of bioinformatics
Discovering alkaline hydrothermal vents
The need for genes
Supercharging the earth's battery through photosynthesis
Rise of the predators
The Krebs cycle in disease