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Explore the critical relationship between material structure and function in downstream bioprocessing through this 26-minute webinar presented by Dr. Thomas F. Johnson. Discover how the design of sustainable materials can enable more efficient purification of emerging biological therapeutics that currently face substantial manufacturing challenges and high costs. Learn about the visualization and characterization of key unit operations across multiple length scales, including conventional approaches like depth filtration, membrane filtration, and packed bed chromatography, as well as innovative solutions such as 3D printed monoliths. Examine how downstream bioprocessing relies on unit operations that exploit chemical and physical properties of biological products for clinical purification applications. Understand the manufacturing issues contributing to the high costs of new therapeutic products entering the clinic and market. Gain insights into how better understanding of structure-function relationships can inform design decisions tailored to specific needs of emergent products and processes. Conclude with a forward-looking vision for essential research activities needed to perfect the downstream bioprocessing design process for more efficient and effective manufacturing of medicines across past, present, and future applications. Earn PACE credits by registering as a Labroots member and completing the viewing requirements before the April 2027 expiration date.
