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Fundamentals and Applications of Supramolecular Chemistry

NPTEL-NOC IITM via YouTube

Overview

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Explore the comprehensive fundamentals and advanced applications of supramolecular chemistry through this extensive lecture series by Prof. Deepak Chopra from IISER Bhopal. Master the core principles of chemical forces including ion-ion, ion-dipole, and dipole-dipole interactions, while developing understanding of van der Waals forces, dispersive interactions, and hydrogen bonding mechanisms. Delve into aromatic interactions, halogen bonding, and sigma-hole directed interactions that govern molecular recognition processes. Learn host-guest complexation principles through detailed study of cyclodextrins, calixarenes, cryptands, and spherands, examining thermodynamic and kinetic selectivity factors. Investigate polymorphism in molecular crystals, cocrystallization processes, and pharmaceutical cocrystal applications with emphasis on characterization techniques and thermodynamic properties. Discover crystal engineering approaches, solid-state reactivity, and nucleation-growth processes in crystallization. Examine self-assembly processes in metal-ligand systems forming complex architectures like racks, grids, ladders, and helicates, including DNA structure formation. Study supramolecular catalysis through self-assembled molecular cages and their applications in organic transformations, along with enzyme mimics and secondary coordination sphere effects. Explore supramolecular photochemistry principles, organocatalysis applications, and photophysical processes in molecular systems. Analyze surfactant chemistry, supramolecular amphiphiles, liquid crystal types and phase transitions, and supramolecular gelators. Investigate molecular machines, stimuli-driven processes, anion and cation binding mechanisms, and ion transport processes in biological systems. Conclude with advanced topics including molecular wires, switches, nonlinear optical materials, supramolecular chirality, systems chemistry, and their practical applications across various fields.

Syllabus

W12L60_Applications of Systems Chemistry
W12L59_Systems Chemistry
W12L58_Supramolecular Chirality
W12L57_Molecular Wire and Cable, Molecular Switches and Non linear optical (NLO) materials
W12L56_Applications in Photophysical processes
W11L55_Supramolecular Photochemistry and Organocatalysis
W11L54_Principles and Applications of Supramolecular Photochemistry
W11L53_Applications of Molecular Barrels, Self Sorting Process
W1152_Applications of Supramolecular Coordination Cages to Organic Transformations
W11L51_Supramolecular Catalysis via Self Assembled Molecular Cages
W10L50_Supramolecular Gelators
W10L49_Liquid Crystals-Types, Structure and Phase transitions in Liquid Crystals
W10L48_Supramolecular Amphiphiles-Structure and Applications
W10L47_Properties, Structures and Phase Diagram of Surfactants
W10L46_Supramolecular chemistry of surfactants
W9L45_Role of Secondary Coordination Sphere in Chemical Transformations
W9L44_Design of Enzyme Mimics
W9L42_Self Assembly in Helicates, Formation and Structure of DNA
W9L42_Self Assembly in Metal-Ligand systems forming Racks, Grids and Ladders
W9L41_Self Assembly Processes
W8L40_Ion transport processes
W8L39_Anion binding in Proteins and Transport processes in biology
W8L38_Examples of anion binding
W8L37_Supramolecular chemistry of complexation of Anions
W8L36_Supramolecular chemistry of complexation of Organic Cations
W7L35_Stimuli Driven Processes in Artificial Molecular Machines
W7L34_Stimuli Driven Processes in Molecular Crystals
W7L33_Types of Phase Transition
W7L32_Nucleation Model, Kinetic and Thermodynamic Crystal, Phase Transitions
W7L31_Understand Nucleation and Growth processes in Crystallization
W6L30_Properties of Pharmaceutical Cocrystals
W6L29_Case Studies on Polymorphism, Cocrystallization, Applications to Pharmaceutical Cocrystals
W6L28_Properties and Thermodynamics of Polymorphism
W6L27_Characterization of Polymorphs
W6L26_Polymorphism in Molecular Crystals
W5L21_Host Guest Complexation in Clathrates, Properties of Gas Hydrates
W5L25_Solid State Reactivity and Topology of H-bonded solids
W5L24_Crystal Engineering, Chemical Reaction in Solids
W5L23_Supramolecular Host Strategy: Trimesic Acid and Dianin's Compound
W5L22_Structures of Gas Hydrates
W4L20_Host Guest Complexation in Cyclodextrins
W4L19_Host Guest Complexation in Calixarenes
W4L18_Phase Transfer Catalyst, Kinetic and Thermodynamic Template Effect
W4L17_Cation complexation in cryptands, spherands, Molecular Conformation
W4L16_Cation complexation in podands, corands and lariat ethers
W3L15_Host-Guest Complexation, Thermodynamic and Kinetic Selectivity
W3L14_Thermodynamics of Host-Guest Complexation, Role of Solvent
W3L13_Factors affecting Chelate Effect,Thermodynamics of binding
W3L12_Lock and Key Principle and Chelate Effect
W3L11_Concept of Host and Guest in Supramolecular Chemistry
W2L10_Competition involving interactions in close packing of solids
W2L9_Cation-pai, Role of close packing v/s H-bonding
W2L8_Halogen---pai, anion...pai and cation...pai interactions
W2L6_Aromatic Interactions
W2L7_Understanding of sigma and pai-hole directed interactions
W1L5_Problem solving and examples in Chemical Forces
W1L4_Modelling of Dispersive Interactions, Introduction to H-bonds
W1L3_Van der Waals Radius
W1L2_Induced Dipole and Dispersive Interactions
W1L1_Chemical Forces, Ion-Ion, Ion-Dipole and Dipole-Dipole Interactions
Fundamentals and Applications of Supramolecular Chemistry

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NPTEL-NOC IITM

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