Explore the design, programming, and operation of massively parallel distributed supercomputers in this 33-minute Sidney Fernbach Award Lecture by Torsten Hoefler at SC22. Delve into distributed-memory parallelism using Remote Direct Memory Access through the Message Passing Interface, following Sidney Fernbach's legacy. Gain insights into current supercomputing practices and discover future technological trends and challenges facing the High-Performance Computing (HPC) community in the coming years.