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Explore the critical challenges and solutions in developing sensitive, specific point-of-care diagnostic assays for infectious diseases in this 43-minute webinar presented by Amanda Grimm from GenScript. Learn how to overcome common but often overlooked hurdles in diagnostic development, including reagent quality issues, specificity problems, and reproducibility challenges that prevent rapid pathogen detection at the point of care. Discover strategies for detecting low-abundance pathogens while avoiding cross-reactivity and ensuring consistency from early discovery through scale-up production. Examine real-world applications for respiratory viruses, antimicrobial-resistant bacteria, and complex microbial environments through published examples and case studies. Gain insights into precision-engineered solutions including custom monoclonal antibodies, recombinant antigens, CRISPR enzymes, and NGS-ready oligonucleotides that can improve signal detection, reduce background noise, and accelerate development timelines. Whether developing lateral flow assays, ELISAs, or molecular tests, acquire practical strategies to enhance precision and effectiveness at every stage of assay development, from initial concept through commercial implementation.
