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From Blind Spot to Biomarker - Transforming Brain Health Monitoring with ImmunoPCR

Labroots via YouTube

Overview

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Explore advanced ImmunoPCR technologies for detecting low-abundance protein biomarkers in neurological disorders through this 58-minute webinar. Learn how high-sensitivity immunoassays are revolutionizing the detection of critical brain health indicators including Neurofilament Light (NF-L), Tau, and TNFα in the context of traumatic brain injury, Alzheimer's disease, and related brain conditions. Discover Thermo Fisher Scientific's ImmunoPCR solutions, including the Olink platform for proximity extension assay-based proteomic discovery and the Invitrogen ProQuantum platform for proximity ligation assay-based clinical assay development. Examine Gryphon Bio's proteomic workflow for brain biomarker discovery and their development of proprietary ImmunoPCR reagents for blood-based brain health monitoring tests. Understand how these complementary technologies utilize PCR amplification of oligonucleotide-labeled antibodies to bind protein biomarker targets, offering significant advantages for measuring brain biomarkers in various biofluids. Gain insights into the identification of distinct "waves" of elevated novel brain biomarkers in samples from traumatic brain injury, mild cognitive impairment, and Alzheimer's disease patients, and learn about the development of scalable, cost-effective technologies for longitudinal monitoring of biomarkers from brain cells affected by aging, infection, injury, and disease.

Syllabus

From Blind Spot to Biomarker Transforming Brain Health Monitoring with ImmunoPCR

Taught by

Labroots

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