Multiscale Molecular Modeling of DNA - Toward Simulating Its Naturally Confined Environment

Explore multiscale molecular modeling approaches for DNA simulation in this 70-minute lecture by Francesca Mocci from the University of Cagliari, Italy, presented at the Bogolyubov Institute for Theoretical Physics. Delve into advanced computational methods for modeling DNA structure and dynamics, with particular emphasis on simulating DNA within its naturally confined cellular environment. Learn about the theoretical frameworks and computational techniques used to bridge different length and time scales in molecular modeling, from atomic-level interactions to larger biological systems. Discover how multiscale approaches can provide insights into DNA behavior under various biological conditions and constraints, offering a comprehensive understanding of nucleic acid structure-function relationships in realistic cellular contexts.