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Explore the fundamental principles and applications of cryogenics in this 21-minute research presentation delivered at ICTP-SAIFR's Quantum Technologies Research Group Meeting. Learn about ultra-low temperature physics and the critical role cryogenic systems play in quantum technology applications from Felix Hernandez of USP. Discover how cryogenic cooling enables quantum devices to operate at temperatures near absolute zero, understand the technical challenges of maintaining these extreme conditions, and examine the engineering solutions that make quantum computing and other quantum technologies possible. Gain insights into the intersection of thermal physics and quantum mechanics, including how cryogenic environments minimize thermal noise and preserve quantum coherence in sensitive quantum systems.