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Learn to quantify whether personalized intervention policies provide significantly better outcomes than single best interventions for all individuals in this conference talk. Explore a new statistical estimator that analyzes historical data to determine if personalization offers superior expected results across diverse domains including medicine, marketing, and social sciences. Examine the trade-offs between personalization benefits and associated costs such as logistical challenges, reduced shared context, fairness concerns, and increased data requirements for accurate learning. Discover how personalized policies can be more fragile due to their higher data demands compared to identifying universal best interventions. Review practical applications through four diverse datasets that demonstrate the wide range of settings where quantifying personalization impact proves valuable. Compare the proposed estimator's performance against existing approaches and understand its advantages in bridging prediction and intervention problems in social systems.