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Epithelium Formation: Cellular Adhesion Regulation in 3D

Labroots via YouTube

Overview

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Join Professor Rafael Garcia-Mata from the University of Toledo for a one-hour webinar exploring the intricate molecular mechanisms governing epithelium formation and cellular adhesion in three dimensions. Delve into the critical role of the Scribble complex in establishing apicobasal polarity in epithelial cells and discover how these polarized cell monolayers form barriers that separate internal and external environments. Learn advanced biochemical and imaging techniques used to study cell architecture in both 2D and 3D environments, with particular focus on SGEF-mediated regulation of E-cadherin and ZO-1 in cell-cell junctions. Master the fundamentals of lumen formation in 3D epithelial cysts and gain practical knowledge about adherens junction and tight junction regulation in epithelial cells. Drawing from his extensive research background and over 50 high-impact publications, Dr. Garcia-Mata shares insights into cell adhesion, migration, and invasion mechanisms relevant to both normal and cancer cells.

Syllabus

Epithelium Formation: Cellular Adhesion Regulation in 3D

Taught by

Labroots

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