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This lecture explains the causes and diagnostic work-up of elevated anion gap metabolic acidosis, including lactate, ketoacids, renal failure, and toxic exposures. It also discusses the serum osmolal gap.
Syllabus
Intro
Learning Objectives
Etiologies of an Elevated Gap Acidosis
Formation of Lactate
Sources and Elimination of Lactate
Medications and Toxins Associated with Lactic Acidosis
D-Lactic Acidosis
Ketoacidosis
Formation of ketoacids
Acidosis in Renal Failure
Methanol
Ethylene Glycol
Propylene Glycol
Serum Osmolal Gap
Toluene
Taught by
Strong Medicine